{"id":8698,"date":"2022-08-21T15:01:56","date_gmt":"2022-08-21T18:01:56","guid":{"rendered":"https:\/\/miradouronoticias.com\/site\/?p=8698"},"modified":"2022-08-21T15:01:56","modified_gmt":"2022-08-21T18:01:56","slug":"pesquisa-mostra-eficacia-da-vitamina-b12-para-atenuar-covid-19","status":"publish","type":"post","link":"https:\/\/miradouronoticias.com\/site\/2022\/08\/21\/pesquisa-mostra-eficacia-da-vitamina-b12-para-atenuar-covid-19\/","title":{"rendered":"Pesquisa mostra efic\u00e1cia da vitamina B12 para atenuar covid-19"},"content":{"rendered":"

Estudo foi conduzido pela Fiocruz Minas Gerais<\/h3>\n
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Ou\u00e7a a mat\u00e9ria:<\/h4>\n

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Estudo da Funda\u00e7\u00e3o Oswaldo Cruz (Fiocruz) Minas Gerais constatou que a vitamina B12 regula processos inflamat\u00f3rios que, durante a infec\u00e7\u00e3o pelo v\u00edrus Sars-CoV-2, se encontram desregulados e levam ao agravamento da covid-19.<\/p>\n

A pesquisa comparou amostras de sangue de pacientes hospitalizados com as formas grave e moderada da doen\u00e7a com amostras de sangue de pessoas saud\u00e1veis (volunt\u00e1rios sem covid-19), analisando a express\u00e3o de todos os genes pelas c\u00e9lulas de defesa, os leuc\u00f3citos, em cada um dos grupos.<\/p>\n

Segundo o estudo, as an\u00e1lises mostraram que os pacientes com covid-19 tinham express\u00e3o alterada de muitos genes, embora estivessem em tratamento com corticoides h\u00e1 cerca de 11 dias. Com a introdu\u00e7\u00e3o da vitamina B12, a express\u00e3o dos genes inflamat\u00f3rios e de resposta antiviral dos pacientes se aproximou \u00e0 dos indiv\u00edduos saud\u00e1veis, mostrando a efic\u00e1cia da vitamina para o controle da inflama\u00e7\u00e3o.<\/p>\n

Todos os dados gerados pela pesquisa foram\u00a0publicados em um artigo, em formato ainda em preprint<\/a>, enquanto \u00e9 aguardado o processo de revis\u00e3o pelos pares que antecede a publica\u00e7\u00e3o da vers\u00e3o definitiva.<\/p>\n

De acordo com o estudo, a B12 atenua um quadro conhecido como tempestade inflamat\u00f3ria, causado por uma resposta imune excessiva do organismo. A B12 atua como um regulador desse evento, ao aumentar a produ\u00e7\u00e3o da mol\u00e9cula doadora universal de uma subst\u00e2ncia chamada metil, capaz de desativar genes que favorecem a inflama\u00e7\u00e3o.<\/p>\n

A pesquisa da Fiocruz Minas mostra, de forma pioneira, que \u00e9 poss\u00edvel atuar na normaliza\u00e7\u00e3o\u00a0desse processo que, por sua vez, \u00e9 fundamental para a regula\u00e7\u00e3o\u00a0da atividade dos genes por meio de f\u00e1rmacos, no caso, a vitamina B12.<\/p>\n

De acordo com a Fiocruz, para verificar a seguran\u00e7a da B12, a equipe da pesquisa introduziu o tratamento com a vitamina nas amostras de indiv\u00edduos saud\u00e1veis e constatou que n\u00e3o houve qualquer altera\u00e7\u00e3o nos n\u00edveis de express\u00e3o dos genes avaliados o que mostra a seguran\u00e7a do tratamento, ao atestar a n\u00e3o toxidade da B12, e comprova a efici\u00eancia da vitamina especificamente para a regula\u00e7\u00e3o dos genes com express\u00e3o alterada na covid-19.<\/p>\n

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Segundo o pesquisador Roney Coimbra, coordenador do estudo, n\u00e3o adianta tomar a vitamina por conta pr\u00f3pria, como medida de preven\u00e7\u00e3o, uma vez que a pesquisa s\u00f3 constatou a efici\u00eancia da B12 para a normaliza\u00e7\u00e3o de processos inflamat\u00f3rios alterados pela doen\u00e7a.<\/p>\n

A pesquisa foi realizada em parceria com o Hospital Metropolitano Dr. C\u00e9lio de Castro, em Belo Horizonte, onde foram recrutados os pacientes para o fornecimento das amostras, al\u00e9m dos dados cl\u00ednicos e laboratoriais necess\u00e1rios para as an\u00e1lises. O estudo contou ainda com a participa\u00e7\u00e3o de pesquisadores da Universidade Federal de S\u00e3o Paulo (Unifesp) e da Universidade Federal de Minas Gerais (UFMG).<\/p>\n

\"\"
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*Edi\u00e7\u00e3o: L\u00edlian Beraldo<\/h5>\n<\/div>\n<\/div>\n<\/div>\n
Ag\u00eancia Brasil<\/strong><\/h6>\n
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By: miradouronot\u00edcias.com.br<\/span><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

Estudo foi conduzido pela Fiocruz Minas Gerais Ou\u00e7a a mat\u00e9ria: Estudo da Funda\u00e7\u00e3o Oswaldo Cruz (Fiocruz) Minas Gerais constatou que a vitamina B12 regula processos inflamat\u00f3rios que, durante a infec\u00e7\u00e3o pelo v\u00edrus Sars-CoV-2, se encontram desregulados e levam ao agravamento da covid-19. A pesquisa comparou amostras de sangue de pacientes hospitalizados com as formas grave […]<\/p>\n","protected":false},"author":4,"featured_media":8699,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[19,9,22],"tags":[],"class_list":["post-8698","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cidade","category-destaque-1","category-saude"],"yoast_head":"\nPesquisa mostra efic\u00e1cia da vitamina B12 para atenuar covid-19 - Miradouro Not\u00edcias<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/miradouronoticias.com\/site\/2022\/08\/21\/pesquisa-mostra-eficacia-da-vitamina-b12-para-atenuar-covid-19\/\" \/>\n<meta property=\"og:locale\" content=\"pt_BR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pesquisa mostra efic\u00e1cia da vitamina B12 para atenuar covid-19 - Miradouro Not\u00edcias\" \/>\n<meta property=\"og:description\" content=\"Estudo foi conduzido pela Fiocruz Minas Gerais Ou\u00e7a a mat\u00e9ria: Estudo da Funda\u00e7\u00e3o Oswaldo Cruz (Fiocruz) Minas Gerais constatou que a vitamina B12 regula processos inflamat\u00f3rios que, durante a infec\u00e7\u00e3o pelo v\u00edrus Sars-CoV-2, se encontram desregulados e levam ao agravamento da covid-19. 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